Activation of rodent AP and NTS Calcr neurons acutely reduces food intake and body weight 12,13 , while AP lesions attenuate acute amylin-induced suppression of food intake 9
The session highlighted concerns that: Appetite suppression may mask eating disorder symptoms Weight loss may be misinterpreted as clinical improvement Binge eating disorder may be misdiagnosed, particularly in larger-bodied individuals It is necessary to emphasize the importance of careful screening and ongoing assessment
Study overview: Researchers from Alliance Medical (Europe) analyzed oncologic PET-CT scans in patients receiving GLP-1 therapy and observed abnormal fluorodeoxyglucose (FDG) uptake patterns that could easily be mistaken for pathological hot spots. In some cases, what appears to be malignant metabolic activity may, in fact, represent drug-induced metabolic redistributionlikely linked to delayed gastric emptying and altered glucose metabolism caused by GLP-1 agonism
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An advisory group is guiding the government's response to the so-called Health Technology Assessment (HTA) review, but Ms de Somer said the latest stalemate over Mounjaro highlighted the need for more urgent action